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Applied and Environmental Microbiology, May 2008, p. 3315-3318, Vol. 74, No. 10
0099-2240/08/$08.00+0     doi:10.1128/AEM.02148-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Use of Murine Norovirus as a Surrogate To Evaluate Resistance of Human Norovirus to Disinfectants{triangledown}

Gaël Belliot,* Amandine Lavaux, Donya Souihel, Davide Agnello, and Pierre Pothier

Laboratoire de Virologie, Centre National de Référence des Virus Entériques, Centre Hospitalier Universitaire de Dijon, 7 boulevard Jeanne d'Arc, 21079 Dijon Cedex, France

Received 19 September 2007/ Accepted 23 March 2008

Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.

* Corresponding author. Mailing address: Laboratoire de Virologie, Centre National de Référence des Virus Entériques, Centre Hospitalier Universitaire de Dijon, 7 boulevard Jeanne d'Arc, 21079 Dijon Cedex, France. Phone: (33) 3-80-29-31-70. Fax: (33) 3-80-29-36-04. E-mail: gael.belliot{at}u-bourgogne.fr

{triangledown} Published ahead of print on 31 March 2008.

Applied and Environmental Microbiology, May 2008, p. 3315-3318, Vol. 74, No. 10
0099-2240/08/$08.00+0     doi:10.1128/AEM.02148-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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