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Applied and Environmental Microbiology, July 2008, p. 4564-4566, Vol. 74, No. 14
0099-2240/08/$08.00+0     doi:10.1128/AEM.02528-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Therapeutic Supplementation of Caprylic Acid in Feed Reduces Campylobacter jejuni Colonization in Broiler Chicks {triangledown}

F. Solis de los Santos,1 A. M. Donoghue,2 K. Venkitanarayanan,3 I. Reyes-Herrera,1 J. H. Metcalf,1 M. L. Dirain,1 V. F. Aguiar,1 P. J. Blore,1 and D. J. Donoghue1*

Poultry Science Department, University of Arkansas, Fayetteville, Arkansas 72701,1 Poultry Production and Product Safety Research Unit, Agricultural Research Service, USDA, Fayetteville, Arkansas 72701,2 Department of Animal Science, University of Connecticut, Storrs, Connecticut 062693

Received 8 November 2007/ Accepted 12 May 2008

Poultry colonized with Campylobacter species are a significant source of human food-borne illness. The therapeutic use of the medium chain fatty acid caprylic acid consistently reduced enteric C. jejuni colonization in chicks by 3 to 4 logs in three separate trials. These results support caprylic acid's potential to reduce Campylobacter carriage in poultry.


* Corresponding author. Mailing address: POSC O-408, 1260 W. Maple St., University of Arkansas, Fayetteville, AR 72701. Phone: (479) 575-2913. Fax: (479) 575-4202. E-mail: ddonogh{at}uark.edu

{triangledown} Published ahead of print on 23 May 2008.


Applied and Environmental Microbiology, July 2008, p. 4564-4566, Vol. 74, No. 14
0099-2240/08/$08.00+0     doi:10.1128/AEM.02528-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • de los Santos, F. S., Donoghue, A. M., Venkitanarayanan, K., Metcalf, J. H., Reyes-Herrera, I., Dirain, M. L., Aguiar, V. F., Blore, P. J., Donoghue, D. J. (2009). The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. Poult. Sci. 88: 61-64 [Abstract] [Full Text]