This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Giaouris, E.
Right arrow Articles by Chapot-Chartier, M.-P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Giaouris, E.
Right arrow Articles by Chapot-Chartier, M.-P.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*(L)-ALANINE
Medline Plus Health Information
*Antibiotics
Agricola
Right arrow Articles by Giaouris, E.
Right arrow Articles by Chapot-Chartier, M.-P.

 Previous Article  |  Next Article 

Applied and Environmental Microbiology, August 2008, p. 4764-4767, Vol. 74, No. 15
0099-2240/08/$08.00+0     doi:10.1128/AEM.00078-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Variations in the Degree of D-Alanylation of Teichoic Acids in Lactococcus lactis Alter Resistance to Cationic Antimicrobials but Have No Effect on Bacterial Surface Hydrophobicity and Charge{triangledown}

Efstathios Giaouris,1,2,{dagger} Romain Briandet,2 Mickael Meyrand,1 Pascal Courtin,1 and Marie-Pierre Chapot-Chartier1*

INRA, UR477 Biochimie Bactérienne, F-78350 Jouy-en-Josas, France,1 INRA-AgroParisTech, UMR 763 Bioadhesion et Hygiène des Matériaux, 25 avenue de la République, F-91300 Massy, France2

Received 10 January 2008/ Accepted 29 May 2008

An increase of the degree of D-alanylation of teichoic acids in Lactococcus lactis resulted in a significant increase of bacterial resistance toward the cationic antimicrobials nisin and lysozyme, whereas the absence of D-alanylation led to a decreased resistance toward the same compounds. In contrast, the same variations of the D-alanylation degree did not modify bacterial cell surface charge and hydrophobicity. Bacterial adhesion to polystyrene and glass surfaces was not modified either.

* Corresponding author. Mailing address: INRA, Unité de Biochimie Bactérienne, Domaine de Vilvert, 78352 Jouy-en-Josas Cedex, France. Phone: 33 1 34 65 22 68. Fax: 33 1 34 65 21 63. E-mail: Marie-Pierre.Chapot{at}jouy.inra.fr

{triangledown} Published ahead of print on 6 June 2008.

{dagger} Present address: Laboratory of Microbiology and Biotechnology of Foods, Department of Food Science and Technology, Agricultural University of Athens, Athens, Greece.

Applied and Environmental Microbiology, August 2008, p. 4764-4767, Vol. 74, No. 15
0099-2240/08/$08.00+0     doi:10.1128/AEM.00078-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Veiga, P., Erkelenz, M., Bernard, E., Courtin, P., Kulakauskas, S., Chapot-Chartier, M.-P. (2009). Identification of the Asparagine Synthase Responsible for D-Asp Amidation in the Lactococcus lactis Peptidoglycan Interpeptide Crossbridge. J. Bacteriol. 191: 3752-3757 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»