This Article Full Text Full Text (PDF) Other Versions of this Article: AEM.00514-08v1 74/16/5244    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Google Scholar Articles by Gross, G. Articles by Snel, J. PubMed PubMed Citation Articles by Gross, G. Articles by Snel, J. Agricola Articles by Gross, G. Articles by Snel, J.

 Previous Article  |  Next Article 

Applied and Environmental Microbiology, August 2008, p. 5244-5249, Vol. 74, No. 16
0099-2240/08/$08.00+0     doi:10.1128/AEM.00514-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Probiotic Lactobacillus plantarum 299v Does Not Counteract Unfavorable Phytohemagglutinin-Induced Changes in the Rat Intestinal Microbiota

Gabriele Gross,^1,2, Jessica Wildner,^1, Arjan Schonewille,¹ Jan L. W. Rademaker,¹ Roelof van der Meer,¹ and Johannes Snel^1*

Department Health and Safety, NIZO food research, P.O. Box 20, 6710 BA Ede, The Netherlands,¹ Animal Breeding and Genomics Centre, Animal Sciences Group of Wageningen UR, P.O. Box 65, 8200 AB Lelystad, The Netherlands²

Received 3 March 2008/ Accepted 24 June 2008

Application of phytohemagglutinin (PHA) in weaning feed has been suggested to stimulate intestinal epithelium maturation. In this study, PHA strongly affected the fecal bacterial population structure of rats. Escherichia coli overgrowth was not prevented by probiotic mannose-adhering Lactobacillus plantarum 299v. Therefore, use of PHA in weaning feed deserves careful evaluation.

Published ahead of print on 7 July 2008.

Present address: LabMET, Ghent University, Ghent, Belgium.

Present address: ttz, Bremerhaven, Germany.