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Applied and Environmental Microbiology, September 2008, p. 5817-5821, Vol. 74, No. 18
0099-2240/08/$08.00+0     doi:10.1128/AEM.00225-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Genetic Diversity of Porphyromonas gingivalis Isolates Recovered from Single "Refractory" Periodontitis Sites{triangledown}

Morten Enersen,1,2* Ingar Olsen,1 and Dominique A. Caugant1,2

Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway,1 Department of Bacteriology and Immunology, Norwegian Institute of Public Health, 0403 Oslo, Norway2

Received 20 January 2008/ Accepted 11 July 2008

Multilocus sequence typing and fimA genotyping were performed on Porphyromonas gingivalis isolates from 15 subjects with "refractory" periodontitis. Several sequence types were detected for most individual pockets. The variation indicated recombination at the recA and pepO genes. The prevalence of fimA genotypes II and IV confirmed their association with periodontitis.

* Corresponding author. Mailing address: Institute of Oral Biology, Faculty of Dentistry, University of Oslo, P.O. Box 1052, NO-0316 Oslo, Norway. Phone: 47 22840353. Fax: 47 22840301. E-mail: morteene{at}odont.uio.no

{triangledown} Published ahead of print on 18 July 2008.

Applied and Environmental Microbiology, September 2008, p. 5817-5821, Vol. 74, No. 18
0099-2240/08/$08.00+0     doi:10.1128/AEM.00225-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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