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Applied and Environmental Microbiology, October 2008, p. 6158-6160, Vol. 74, No. 19
0099-2240/08/$08.00+0     doi:10.1128/AEM.02872-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Recovery and Sequence Analysis of Hepatitis A Virus from Springwater Implicated in an Outbreak of Acute Viral Hepatitis{triangledown}

Lindsay A. Tallon,1,2* David C. Love,2 Zack S. Moore,3 and Mark D. Sobsey2

North Carolina Center for Public Health Preparedness, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599,1 Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599,2 Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, and North Carolina Department of Health and Human Services, Raleigh, North Carolina 276993

Received 19 December 2007/ Accepted 5 August 2008

An outbreak of acute hepatitis A virus in North Carolina was linked to drinking water from a contaminated shallow spring by phylogenetic analysis of hepatitis A virus (HAV) genomic sequences. Detection of HAV and fecal indicators in the water provided useful and timely information to assist with public health prevention and control measures.

* Corresponding author. Present address: Harvard School of Public Health, Division of Public Health Practice, 677 Huntington Ave., Boston, MA 02115. Phone: (617) 998-1075. Fax: (617) 495-8543. E-mail: ltallon{at}hsph.harvard.edu

{triangledown} Published ahead of print on 15 August 2008.

Applied and Environmental Microbiology, October 2008, p. 6158-6160, Vol. 74, No. 19
0099-2240/08/$08.00+0     doi:10.1128/AEM.02872-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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