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Applied and Environmental Microbiology, November 2008, p. 7064-7066, Vol. 74, No. 22
0099-2240/08/$08.00+0     doi:10.1128/AEM.01810-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

csrA Inhibits the Formation of Biofilms by Vibrio vulnificus{triangledown}

Melissa K. Jones, Elizabeth B. Warner, and James D. Oliver*

Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223

Received 5 August 2008/ Accepted 16 September 2008

PCR screening of the shellfish-borne pathogen Vibrio vulnificus revealed csrA-negative strains, and these strains formed increased biofilm compared to csrA-positive strains. Complementation in trans with csrA resulted in reduced biofilm formation, similar to that by csrA+ strains. Our results provide evidence that csrA inhibits biofilm formation in V. vulnificus.

* Corresponding author. Mailing address: Department of Biology, University of North Carolina at Charlotte, Charlotte, NC 28223. Phone: (704) 687-8516. Fax: (704) 687-3457. E-mail: jdoliver{at}uncc.edu

{triangledown} Published ahead of print on 26 September 2008.

Applied and Environmental Microbiology, November 2008, p. 7064-7066, Vol. 74, No. 22
0099-2240/08/$08.00+0     doi:10.1128/AEM.01810-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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