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Applied and Environmental Microbiology, November 2008, p. 7094-7097, Vol. 74, No. 22
0099-2240/08/$08.00+0     doi:10.1128/AEM.01378-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Identification of a Novel Genomic Island Specific to Hospital-Acquired Clonal Complex 17 Enterococcus faecium Isolates{triangledown} ,{dagger}

Esther Heikens,* Willem van Schaik, Helen L. Leavis, Marc J. M. Bonten, and Rob J. L. Willems

Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

Received 19 June 2008/ Accepted 21 September 2008

Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.

* Corresponding author. Mailing address: Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. Phone: 31 88 7555006. Fax: 31 30 2541770. E-mail: E.heikens{at}umcutrecht.nl

{triangledown} Published ahead of print on 3 October 2008.

{dagger} Supplemental material for this article may be found at http://aem.asm.org/.

Applied and Environmental Microbiology, November 2008, p. 7094-7097, Vol. 74, No. 22
0099-2240/08/$08.00+0     doi:10.1128/AEM.01378-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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