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Applied and Environmental Microbiology, April 2008, p. 2544-2549, Vol. 74, No. 8
0099-2240/08/$08.00+0     doi:10.1128/AEM.02477-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Tracing of Norovirus Outbreak Strains in Mussels Collected near Sewage Effluents{triangledown}

Nancy P. Nenonen,1* Charles Hannoun,1 Peter Horal,1 Bodil Hernroth,2 and Tomas Bergström1

Department of Infectious Diseases/Clinical Virology, University of Gothenburg, Guldhedsgatan 10b, 413 46 Gothenburg, Sweden,1 The Royal Swedish Academy of Sciences, Sven Loven Centre for Marine Sciences, Kristineberg 566, SE-450 34 Fiskebäckskil, Sweden2

Received 2 November 2007/ Accepted 20 February 2008

Noroviruses from mussels collected near sewage effluents were compared with local patient outbreak strains. Sequence analyses of RNA polymerase-capsid-poly(A)-3' (3.1-kilobase) regions confirmed the 99.9% similarity between genotype I.1 strains from mussels and patient strains from recreational-bathing outbreaks, indicating the potential usefulness of sentinel norovirus mussel studies in tracing human norovirus contamination of coastal waters.

* Corresponding author. Mailing address: Department of Infectious Diseases/Clinical Virology, University of Gothenburg, Guldhedsgatan 10b, 413 46 Gothenburg, Sweden. Phone: 46 736 601 740. Fax: 46 31827032. E-mail: nancy.nenonen{at}microbio.gu.se

{triangledown} Published ahead of print on 29 February 2008.

Applied and Environmental Microbiology, April 2008, p. 2544-2549, Vol. 74, No. 8
0099-2240/08/$08.00+0     doi:10.1128/AEM.02477-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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