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Applied and Environmental Microbiology, July 2009, p. 4887-4891, Vol. 75, No. 14
0099-2240/09/$08.00+0     doi:10.1128/AEM.00394-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Probiotic Properties of the 2-Substituted (1,3)-β-D-Glucan-Producing Bacterium Pediococcus parvulus 2.6{triangledown}

Pilar Fernández de Palencia,1,2 María Laura Werning,1 Elena Sierra-Filardi,1 María Teresa Dueñas,3 Ana Irastorza,3 Angel L. Corbí,1 and Paloma López1*

Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain,1 Instituto del Frío, CSIC, José Antonio Novais 10, 28040 Madrid, Spain,2 Departamento de Química Aplicada, Facultad de Ciencias Químicas, Box 1072, 20080 San Sebastian, Spain3

Received 17 February 2009/ Accepted 14 May 2009

Exopolysaccharides have prebiotic potential and contribute to the rheology and texture of fermented foods. Here we have analyzed the in vitro bioavailability and immunomodulatory properties of the 2-substituted (1,3)-β-D-glucan-producing bacterium Pediococcus parvulus 2.6. It resists gastrointestinal stress, adheres to Caco-2 cells, and induces the production of inflammation-related cytokines by polarized macrophages.

* Corresponding author. Mailing address: Centro de Investigaciones Biológicas, Ramiro de Maeztu 9, 28040 Madrid, Spain. Phone: 34-918373112. Fax: 34-915360432. E-mail: plg{at}cib.csic.es

{triangledown} Published ahead of print on 22 May 2009.

Applied and Environmental Microbiology, July 2009, p. 4887-4891, Vol. 75, No. 14
0099-2240/09/$08.00+0     doi:10.1128/AEM.00394-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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