This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental material
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Google Scholar
Right arrow Articles by Margos, G.
Right arrow Articles by Kurtenbach, K.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Margos, G.
Right arrow Articles by Kurtenbach, K.
Agricola
Right arrow Articles by Margos, G.
Right arrow Articles by Kurtenbach, K.

 Previous Article  |  Next Article 

Applied and Environmental Microbiology, August 2009, p. 5410-5416, Vol. 75, No. 16
0099-2240/09/$08.00+0     doi:10.1128/AEM.00116-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

A New Borrelia Species Defined by Multilocus Sequence Analysis of Housekeeping Genes{triangledown} ,{dagger}

Gabriele Margos,1* Stephanie A. Vollmer,1 Muriel Cornet,2 Martine Garnier,2 Volker Fingerle,3 Bettina Wilske,4,§ Antra Bormane,5 Liliana Vitorino,6 Margarida Collares-Pereira,6 Michel Drancourt,7 and Klaus Kurtenbach1,{ddagger}

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom,1 Centre National de Référence des Borrelia, Institut Pasteur, 75724 Paris Cedex 15, France,2 National Reference Center for Borrelia, Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit (LGL), Branch Oberschleißheim, Veterinärstrasse 2, 85764 Oberschleißheim, Germany,3 National Reference Center for Borreliae, Max von Pettenkofer Institute, University of Munich, Pettenkofer-Strasse 9a, D80336 Munich, Germany,4 State Agency Public Health Agency, Klijanu Str. 7, LV-1012 Riga, Latvia,5 Unidade de Leptospirose e Borreliose de Lyme, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, R. da Junqueira 96, 1349-008 Lisbon, Portugal,6 Unité des Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS-IRD 6236, IFR48, Faculté de Médecine, Université de la Mediterranée, Marseille, France7

Received 17 January 2009/ Accepted 30 May 2009

Analysis of Lyme borreliosis (LB) spirochetes, using a novel multilocus sequence analysis scheme, revealed that OspA serotype 4 strains (a rodent-associated ecotype) of Borrelia garinii were sufficiently genetically distinct from bird-associated B. garinii strains to deserve species status. We suggest that OspA serotype 4 strains be raised to species status and named Borrelia bavariensis sp. nov. The rooted phylogenetic trees provide novel insights into the evolutionary history of LB spirochetes.

* Corresponding author. Mailing address: Department of Biology and Biochemistry, University of Bath, 3 South, Claverton Down, Bath BA2 7AY, United Kingdom. Phone: 44-1225-385116. Fax: 44-1225-386779. E-mail: gm250{at}bath.ac.uk

{triangledown} Published ahead of print on 19 June 2009.

{dagger} Supplemental material for this article may be found at http://aem.asm.org/.

§ Present address: Harthauser Strasse 8b, D81545 Munich, Germany.

{ddagger} Deceased. This work is dedicated to his memory.

Applied and Environmental Microbiology, August 2009, p. 5410-5416, Vol. 75, No. 16
0099-2240/09/$08.00+0     doi:10.1128/AEM.00116-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»