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Applied and Environmental Microbiology, March 2009, p. 1740-1744, Vol. 75, No. 6
0099-2240/09/$08.00+0     doi:10.1128/AEM.01795-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Isolation of a Human Intestinal Bacterium Capable of Daidzein and Genistein Conversion{triangledown}

Anastasia Matthies, Michael Blaut, and Annett Braune*

Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany

Received 4 August 2008/ Accepted 6 January 2009

A rod-shaped gram-positive anaerobic bacterium, strain HE8, was isolated from human feces. The isolate was able to convert the isoflavones daidzein and genistein to equol and 5-hydroxy-equol, respectively. Based on phenotypic and phylogenetic analyses, strain HE8 is described as a new species, Slackia isoflavoniconvertens.

* Corresponding author. Mailing address: Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany. Phone: 49-33200-88402. Fax: 49-33200-88407. E-mail: braune{at}dife.de

{triangledown} Published ahead of print on 9 January 2009.

Applied and Environmental Microbiology, March 2009, p. 1740-1744, Vol. 75, No. 6
0099-2240/09/$08.00+0     doi:10.1128/AEM.01795-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



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