
Identification of the Biosynthetic Gene Cluster and an Additional Gene for Resistance to the Antituberculosis Drug Capreomycin
Appl. Environ. Microbiol. Felnagle et al.
73: 4162
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
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Table S1: summary of the ORFs contained on the sequenced cosmid that are not proposed to be involved in the biosynthesis of the antituberculosis drug capreomycin.
MS Word document, 45K.
- Supplemental file 2
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Figure S1: summary of the biosynthetic pathways for three nonproteinogenic amino acids incorporated into the capreomycin structure. The pathways were previously proposed for viomycin biosynthesis; this figure highlights the enzymes involved in this process for capreomycin biosynthesis.
Zipped TIF document, 20K.
- Supplemental file 3
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Legend to Fig. S1.
MS Word document, 20K.