Files in this Data Supplement:

• Supplemental file 1 - Peptide-dependent modification, processing, and transport (Table S1); LtnM2T transports, processes, and modifies the natural substrate peptide LtnA2 (Fig. S1); LtnM2T transports, processes, and modifies peptides unrelated to LtnA2 (Fig. S2); LtnT transports and processes peptides in the absence of modification enzymes (Fig. S3); NisC correctly cyclizes peptides encoded by pNZ31 (Fig. S4); identical dehydration extents in the absence of thioether rings by NisBTC and NisBT (Fig. S5); secretion of peptides via NisBT and NisBTC (Fig. S6).
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