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Appl Environ Microbiol. 1968 December; 16(12): 1879-1880
Copyright © 1968 American Society for Microbiology. All Rights Reserved.

Antimicrobial Evaluation of 1-Methyl-3-Nitro-1-Nitrosoguanidine

D. E. Hunt and R. F. Pittillo

Kettering-Meyer Laboratories,1 Southern Research Institute, Birmingham, Alabama 35205

ABSTRACT

1-Methyl-3-nitro-1-nitrosoguanidine was shown to have in vitro antimicrobial activity against fungi and gram-positive and gram-negative bacteria; it was also shown to have in vivo activity in mice experimentally infected with Staphylococcus aureus or Escherichia coli comparable to that observed with penicillin or streptomycin sulfate.

FOOTNOTES

1 Affiliated with the Sloan-Kettering Institute for Cancer Research, New York, N.Y.

Appl Environ Microbiol. 1968 December; 16(12): 1879-1880
Copyright © 1968 American Society for Microbiology. All Rights Reserved.





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Copyright © 1968 by the American Society for Microbiology. All rights reserved.