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Appl Environ Microbiol. 1972 June; 23(6): 1121-1124
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Equine Abortion (Herpes) Virus: Strain Differences in Susceptibility to Inactivation by Dithiothreitol

B. Klingeborn1 and Z. Dinter1

Institute of Virology, Royal Veterinary College, Stockholm, Sweden
National Veterinary Institute, Stockholm, Sweden
The Wallenberg Laboratory, University of Uppsala, Uppsala, Sweden

ABSTRACT

The infectivity of equine abortion (herpes) virus (EAV) was inactivated by treatment with reduced dithiothreitol (DTT). According to their susceptibility to DTT, the EAV strains could be divided into three groups. The vaccine strain RAC-H (419) proved to be more resistant to DTT than all of the other 14 strains tested. The hemagglutinin of EAV was also inactivated by DTT; no strain differences were observed in this respect.


Appl Environ Microbiol. 1972 June; 23(6): 1121-1124
Copyright © 1972 American Society for Microbiology. All Rights Reserved.