This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Powell, J. W. Articles by Wachsman, J. T. Search for Related Content PubMed Articles by Powell, J. W. Articles by Wachsman, J. T. Agricola Articles by Powell, J. W. Articles by Wachsman, J. T.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1973 June; 25(6): 869-872
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Evidence for Four Deoxynucleoside Kinase Activities in Extracts of Lactobacillus leichmannii

¹ Department of Microbiology, University of Illinois, Urbana, Illinois 61801

ABSTRACT

Extracts of Lactobacillus leichmannii (ATCC 7830) catalyze the phosphorylation of the four principal deoxynucleosides. Thymidine, deoxyguanosine, and deoxycytidine kinase activities were found to be optimal with deoxyadenosine triphosphate as the phosphoryl donor, whereas deoxycytidine triphosphate was the optimal donor for deoxyadenosine kinase activity. L. leichmannii catalyzes the conversion of deoxycytidine to deoxyuridylic acid, probably by a pathway involving deoxycytidylate deaminase.