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Appl. Environ. Microbiol., Nov 1996, 4206-4209, Vol 62, No. 11
Copyright © 1996, American Society for Microbiology

Degradation of the fluoroquinolone enrofloxacin by wood-rotting fungi

R Martens, HG Wetzstein, F Zadrazil, M Capelari, P Hoffmann and N Schmeer
Bundesforschungsanstalt fur Landwirtschaft, Institut fur Bodenbiologie, Braunschweig, Germany.

The veterinary fluoroquinolone enrofloxacin was degraded in vitro by four species of wood-rotting fungi growing on wetted wheat straw containing carbonyl-14C-labeled drug. A maximum 14CO2 production of 17% per week was observed with the brown rot fungus Gloeophyllum striatum, resulting in up to 53% after 8 weeks. However, rates reached at most 0.2 and 0.9% per week, if enrofloxacin was preadsorbed to native or gamma ray-sterilized soil, respectively.


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