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Appl Environ Microbiol, March 1998, p. 1161-1162, Vol. 64, No. 3
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

A Rapid Method for Screening Large Numbers of Environmental Microorganisms for Antiviral Activity

Carlo Maullu, Giorgio Lampis, Delia Deidda, Sabrina Petruzzelli, and Raffaello Pompei*

Cattedra di Microbiologia Applicata, Università degli Studi di Cagliari, 09124 Cagliari, Italy

Received 22 May 1997/Accepted 9 December 1997

A new method for screening microbial colonies endowed with antiviral activity is described. It is based on close contact between microbial agar cultures and agar-covered virus-infected-cell monolayers and allows the screening of large numbers of colonies in just a few months.


* Corresponding author. Mailing address: Cattedra di Microbiologia Applicata, Università degli Studi di Cagliari, via Porcell 4, 09124 Cagliari, Italy. Phone: 070/6758483. Fax: 070/6758482. E-mail: Rpompei{at}unica.it.