This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Friebe, A.
Right arrow Articles by Sicker, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Friebe, A.
Right arrow Articles by Sicker, D.
Agricola
Right arrow Articles by Friebe, A.
Right arrow Articles by Sicker, D.

 Previous Article  |  Next Article 

Appl Environ Microbiol, July 1998, p. 2386-2391, Vol. 64, No. 7
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Detoxification of Benzoxazolinone Allelochemicals from Wheat by Gaeumannomyces graminis var. tritici, G. graminis var. graminis, G. graminis var. avenae, and Fusarium culmorum

A. Friebe,1,* V. Vilich,2 L. Hennig,3 M. Kluge,3 and D. Sicker3

Institute of Agricultural Botany1 and Institute for Plant Diseases,2 University of Bonn, 53115 Bonn, and Institute of Organic Chemistry, University of Leipzig, 04103 Leipzig,3 Germany

Received 14 July 1997/Accepted 23 April 1998

The ability of phytopathogenic fungi to overcome the chemical defense barriers of their host plants is of great importance for fungal pathogenicity. We studied the role of cyclic hydroxamic acids and their related benzoxazolinones in plant interactions with pathogenic fungi. We identified species-dependent differences in the abilities of Gaeumannomyces graminis var. tritici, Gaeumannomyces graminis var. graminis, Gaeumannomyces graminis var. avenae, and Fusarium culmorum to detoxify these allelochemicals of gramineous plants. The G. graminis var. graminis isolate degraded benzoxazolin-2(3H)-one (BOA) and 6-methoxy-benzoxazolin-2(3H)-one (MBOA) more efficiently than did G. graminis var. tritici and G. graminis var. avenae. F. culmorum degraded BOA but not MBOA. N-(2-Hydroxyphenyl)-malonamic acid and N-(2-hydroxy-4-methoxyphenyl)-malonamic acid were the primary G. graminis var. graminis and G. graminis var. tritici metabolites of BOA and MBOA, respectively, as well as of the related cyclic hydroxamic acids. 2-Amino-3H-phenoxazin-3-one was identified as an additional G. graminis var. tritici metabolite of BOA. No metabolite accumulation was detected for G. graminis var. avenae and F. culmorum by high-pressure liquid chromatography. The mycelial growth of the pathogenic fungi was inhibited more by BOA and MBOA than by their related fungal metabolites. The tolerance of Gaeumannomyces spp. for benzoxazolinone compounds is correlated with their detoxification ability. The ability of Gaeumannomyces isolates to cause root rot symptoms in wheat (cultivars Rektor and Astron) parallels their potential to degrade wheat allelochemicals to nontoxic compounds.

* Corresponding author. Mailing address: Institute of Agricultural Botany, University of Bonn, Meckenheimer Allee 176, 53115 Bonn, Germany. Phone: 49 228 732156. Fax: 49 228 695168. E-mail: ulp50d{at}ibm.rhrz.uni-bonn.de.

Appl Environ Microbiol, July 1998, p. 2386-2391, Vol. 64, No. 7
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Glenn, A. E., Meredith, F. I., Morrison III, W. H., Bacon, C. W. (2003). Identification of Intermediate and Branch Metabolites Resulting from Biotransformation of 2-Benzoxazolinone by Fusarium verticillioides. Appl. Environ. Microbiol. 69: 3165-3169 [Abstract] [Full Text]  
  • Zikmundova, M., Drandarov, K., Bigler, L., Hesse, M., Werner, C. (2002). Biotransformation of 2-Benzoxazolinone and 2-Hydroxy-1,4-Benzoxazin-3-one by Endophytic Fungi Isolated from Aphelandra tetragona. Appl. Environ. Microbiol. 68: 4863-4870 [Abstract] [Full Text]  
  • Glenn, A. E., Hinton, D. M., Yates, I. E., Bacon, C. W. (2001). Detoxification of Corn Antimicrobial Compounds as the Basis for Isolating Fusarium verticillioides and Some Other Fusarium Species from Corn. Appl. Environ. Microbiol. 67: 2973-2981 [Abstract] [Full Text]  
  • Morrissey, J. P., Osbourn, A. E. (1999). Fungal Resistance to Plant Antibiotics as a Mechanism of Pathogenesis. Microbiol. Mol. Biol. Rev. 63: 708-724 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»