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Applied and Environmental Microbiology, September 1998, p. 3512-3514, Vol. 64, No. 9
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Chemostat Production of Plantaricin C By Lactobacillus plantarum LL441

J. M. Bruno Bárcena,1,dagger F. Siñeriz,1,Dagger D. González de Llano,1 Ana Rodríguez,1 and Juan E. Suárez1,2,*

Instituto de Productos Lácteos de Asturias (IPLA-CSIC), 33300 Villaviciosa, Asturias,1 and Área de Microbiología, Facultad de Medicina, Universidad de Oviedo, 33006 Oviedo,2 Spain

Received 7 November 1997/Accepted 5 July 1998

Plantaricin C, a bacteriocin synthesized by Lactobacillus plantarum LL441, was optimally produced in chemostats kept at pH 5.0, 30°C, 150 rpm, and a dilution rate of 0.05 h-1 when glucose was used as carbon source and a dilution rate of 0.10 to 0.12 h-1 when sucrose or fructose was used instead. Production was abolished at high dilution rates, i.e., when the cells grew rapidly in all carbon sources.

* Corresponding author. Mailing address: Área de Microbiología, Facultad de Medicina, Universidad de Oviedo, c/ Julián Clavería s/n, 33006 Oviedo, Spain. Phone: 34 8 510 35 59. Fax: 34 8 510 31 48. E-mail: jsuarez{at}sauron.quimica.uniovi.es.

dagger Present address: PROIMI, 4000 San Miguel de Tucumán, Argentina.

Dagger Present address: PROIMI and Cátedra de Microbiología Superior, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, 4000 San Miguel de Tucumán, Argentina.

Applied and Environmental Microbiology, September 1998, p. 3512-3514, Vol. 64, No. 9
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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