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Applied and Environmental Microbiology, September 1999, p. 4239-4240, Vol. 65, No. 9
0099-2240/99/$04.00+0

Effect of Methodology on the Tuberculocidal Activity of a Glutaraldehyde-Based Disinfectant

J. N. Dauendorffer, C. Laurain, M. Weber, and M. Dailloux*

Laboratoire de Bactériologie, Centre Hospitalier et Universitaire de Nancy, 54511 Vandoeuvre-les-Nancy, France

Received 4 November 1998/Accepted 9 June 1999

Although official guidelines recommend a plate counting method for testing the susceptibility of mycobacteria to disinfectants, manufacturers usually prefer to employ the BACTEC procedure. Data showing that the BACTEC method overestimates the activity of a glutaraldehyde-based disinfectant against Mycobacterium tuberculosis in comparison with a conventional plate counting procedure are presented.

* Corresponding author. Mailing address: Laboratoire de Bactériologie, Centre Hospitalier et Universitaire de Nancy, Route de Neufchateau, 54511 Vandoeuvre-les-Nancy, France. Phone: 33 3 83 15 34 72. Fax: 33 3 83 15 34 74. E-mail: m.dailloux{at}chu_nancy.fr.

Applied and Environmental Microbiology, September 1999, p. 4239-4240, Vol. 65, No. 9
0099-2240/99/$04.00+0




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