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Applied and Environmental Microbiology, August 2000, p. 3639-3641, Vol. 66, No. 8
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Mycophenolic Acid in Silage

Isabell Schneweis, Karsten Meyer, Stefan Hörmansdorfer, and Johann Bauer*

Institute of Animal Hygiene, Faculty of Agriculture and Horticulture, Technische Universität München, 85354 Freising-Weihenstephan, Federal Republic of Germany

Received 22 October 1999/Accepted 31 May 2000

We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 × 103 and 8.9 × 107 (mean, 4.7 × 106) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti, was detected by liquid chromatography-mass spectrometry in 74 (32%) of these samples at levels ranging from 20 to 35,000 (mean, 1,400) µg/kg. This compound has well-known immunosuppressive properties, so feeding with contaminated silage may promote the development of infectious diseases in livestock.

* Corresponding author. Mailing address: Chair of Animal Hygiene, Faculty of Agriculture and Horticulture, Technische Universität München, 85354 Freising-Weihenstephan, Federal Republic of Germany. Phone: 08161-713312. Fax: 08161-714516. E-mail: tierhygiene{at}agrar.tu-muenchen.de.

Applied and Environmental Microbiology, August 2000, p. 3639-3641, Vol. 66, No. 8
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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