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Applied and Environmental Microbiology, September 2000, p. 4139-4141, Vol. 66, No. 9
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Identification and Characteristics of a Novel Burkholderia Strain with Broad-Spectrum Antimicrobial Activity

Cody C. Cain,1 Alexis T. Henry,1 Robert H. Waldo III,1 Lester J. Casida Jr.,2 and Joseph O. Falkinham III1,*

Fralin Biotechnology Center, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0346,1 and Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802-45002

Received 2 March 2000/Accepted 7 July 2000

A Burkholderia strain isolated from soil is capable of inhibiting the growth of bacteria, plant-pathogenic fungi, pathogenic yeasts, and protozoa. Inhibition does not involve cell contact or the presence of living cells, suggesting that at least a substantial portion of the antimicrobial activity is due to the excretion of extracellular compounds.


* Corresponding author. Mailing address: Fralin Biotechnology Center, Virginia Tech, Blacksburg, VA 24061-0346. Phone: (540) 231-5931. Fax: (540) 231-7126. E-mail: jofiii{at}vt.edu.


Applied and Environmental Microbiology, September 2000, p. 4139-4141, Vol. 66, No. 9
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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