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Applied and Environmental Microbiology, December 2002, p. 6416-6420, Vol. 68, No. 12
0099-2240/02/$04.00+0 DOI: 10.1128/AEM.68.12.6416-6420.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
Sakacin G, a New Type of Antilisterial Bacteriocin
L. Simon,1 C. Fremaux,2 Y. Cenatiempo,1 and J. M. Berjeaud1*
Laboratoire de Microbiologie Fondamentale et Appliquée, EA 2224, IBMIG, 86022 Poitiers,1
Rhodia Food, 86220 Dangé Saint-Romain, France2
Received 23 April 2002/
Accepted 2 September 2002
Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2. Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity.
* Corresponding author. Mailing address: Microbiologie Fondamentale et Appliquée, IBMIG, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France. Phone: (33) 5 49 45 40 06. Fax: (33) 5 49 45 35 03. E-mail:
jean-marc.berjeaud{at}univ-poitiers.fr.
Applied and Environmental Microbiology, December 2002, p. 6416-6420, Vol. 68, No. 12
0099-2240/02/$04.00+0 DOI: 10.1128/AEM.68.12.6416-6420.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
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