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Applied and Environmental Microbiology, September 2002, p. 4676-4678, Vol. 68, No. 9
0099-2240/02/$04.00+0     DOI: 10.1128/AEM.68.9.4676-4678.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Escherichia coli O157 and Non-O157 Isolates Are More Susceptible to L-Lactate than to D-Lactate

Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom

Received 22 January 2002/ Accepted 23 May 2002

The antimicrobial effect of L-lactate was much greater than that of D-lactate over a range of concentrations for Escherichia coli O157 and non-O157 strains. Despite this, the intracellular pHs and membrane potentials of L-lactate- and D-lactate-treated cells were similar, suggesting that these factors are not involved in the antimicrobial action of L-lactate.

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