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Applied and Environmental Microbiology, June 2006, p. 4436-4439, Vol. 72, No. 6
0099-2240/06/$08.00+0     doi:10.1128/AEM.02945-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Cellulose Acetate Containing Toluidine Blue and Rose Bengal Is an Effective Antimicrobial Coating when Exposed to White Light

Valérie Decraene, Jonathan Pratten, and Michael Wilson*

Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom

Received 14 December 2005/ Accepted 29 March 2006

Simple methods of reducing the microbial load on surfaces in hospitals are needed to reduce the risk of hospital-associated infections. Here we report on the ability of a cellulose acetate coating containing the photosensitizers toluidine blue and rose bengal to kill microbes (Staphylococcus aureus, Escherichia coli, Clostridium difficile, a bacteriophage, and Candida albicans) on its surface when illuminated with white light.

* Corresponding author. Mailing address: Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, United Kingdom. Phone: 020-7915-1231. Fax: 020-7915-1127. E-mail: m.wilson{at}eastman.ucl.ac.uk.

Applied and Environmental Microbiology, June 2006, p. 4436-4439, Vol. 72, No. 6
0099-2240/06/$08.00+0     doi:10.1128/AEM.02945-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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