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Applied and Environmental Microbiology, June 2006, p. 4446-4449, Vol. 72, No. 6
0099-2240/06/$08.00+0     doi:10.1128/AEM.01924-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Inactivation of Mycobacterium avium subsp. paratuberculosis in Cow's Milk by Means of High Hydrostatic Pressure at Mild Temperatures

Tomás López-Pedemonte,1 Iker Sevilla,2 Joseba M. Garrido,2 Gorka Aduriz,2 Buenaventura Guamis,1 Ramón A. Juste,2 and Artur X. Roig-Sagués1*

Centre Especial de Recerca Planta de Tecnologia dels Aliments, CeRTA, XiT, Departament de Ciència Animal i dels Aliments, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain,1 Instituto Vasco de Investigación y Desarrollo Agrario (NEIKER), Berreaga, 1, 48160 Derio, Bizkaia, Spain2

Received 15 August 2005/ Accepted 26 March 2006

Two strains of Mycobacterium avium subsp. paratuberculosis (3644/02 and ATCC 19698) were inoculated (approximately 6 log CFU/ml) into sterilized milk to evaluate inactivation by high hydrostatic pressure. Reductions of M. avium subsp. paratuberculosis increased with pressure level. Significant differences were also found between M. avium subsp. paratuberculosis strains and between the media used. Average reductions of 4 log CFU/ml after treatment with 500 MPa are comparable to those caused by thermal treatments.

* Corresponding author. Mailing address: Departament de Ciència Animal i dels Aliments, Facultat de Veterinària, Edifici V, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. Phone: (34) 935811460. Fax: (34) 935811494. E-mail: arturxavier.roig{at}uab.es.

Applied and Environmental Microbiology, June 2006, p. 4446-4449, Vol. 72, No. 6
0099-2240/06/$08.00+0     doi:10.1128/AEM.01924-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Wong, S. Y. Y., Grant, I. R., Friedman, M., Elliott, C. T., Situ, C. (2008). Antibacterial Activities of Naturally Occurring Compounds against Mycobacterium avium subsp. paratuberculosis. Appl. Environ. Microbiol. 74: 5986-5990 [Abstract] [Full Text]  


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