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Applied and Environmental Microbiology, August 2008, p. 4969-4972, Vol. 74, No. 15
0099-2240/08/$08.00+0     doi:10.1128/AEM.00558-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Fibrinogen Induces Biofilm Formation by Streptococcus suis and Enhances Its Antibiotic Resistance{triangledown}

Laetitia Bonifait, Louis Grignon, and Daniel Grenier*

Groupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire, Université Laval, Quebec City, Quebec, Canada

Received 7 March 2008/ Accepted 26 May 2008

In this study, we showed that supplementing the culture medium with fibrinogen induced biofilm formation by Streptococcus suis in a dose-dependent manner. Biofilm-grown S. suis cells were much more resistant to penicillin G than planktonic cells. S. suis bound fibrinogen to its surface, a property that likely contributes to biofilm formation.

* Corresponding author. Mailing address: Groupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire, Université Laval, Quebec City, Quebec, Canada G1K 7P4. Phone: (418) 656-7341. Fax: (418) 656-2861. E-mail: Daniel.Grenier{at}greb.ulaval.ca

{triangledown} Published ahead of print on 6 June 2008.

Applied and Environmental Microbiology, August 2008, p. 4969-4972, Vol. 74, No. 15
0099-2240/08/$08.00+0     doi:10.1128/AEM.00558-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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