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Applied and Environmental Microbiology, October 2008, p. 6470-6472, Vol. 74, No. 20
0099-2240/08/$08.00+0     doi:10.1128/AEM.00552-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Gram-Negative Bacterial Lipopolysaccharide Retention by a Positively Charged New-Generation Filter{triangledown}

Ilaria Bononi,1,2 Veronica Balatti,1,2 Soccorso Gaeta,3 and Mauro Tognon1,2*

Department of Morphology and Embryology, Section of Cell Biology and Molecular Genetics, School of Medicine,1 Center of Biotechnology, University of Ferrara, Via Fossato di Mortara 64/B, 44100 Ferrara, Italy,2 GVS SpA, 40069 Zola Predosa, Italy3

Received 7 March 2008/ Accepted 10 August 2008

Removing endotoxins is an important target in the pharmaceutical industry and in clinical practice. A filter introduced into an intravenous line prevents microbiological contamination, but to date no filters have retained bacterial endotoxins. In our study, we assayed a new-generation filter which is able to capture endotoxins from solutions.


* Corresponding author. Mailing address: Department of Morphology and Embryology, Section of Cell Biology and Molecular Genetics, School of Medicine, University of Ferrara, Via Fossato di Mortara 64/B, 44100 Ferrara, Italy. Phone: 39-0532-455538. Fax: 39-0532-455533. E-mail: tgm{at}unife.it

{triangledown} Published ahead of print on 22 August 2008.


Applied and Environmental Microbiology, October 2008, p. 6470-6472, Vol. 74, No. 20
0099-2240/08/$08.00+0     doi:10.1128/AEM.00552-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Ortolano, G., Canonica, F., McAlister, M., Howard, G., Cervia, J., Bononi, I., Balatti, V., Gaeta, S., Tognon, M. (2009). Bacterial Lipopolysaccharide Retention by a Positively Charged Filter. Appl. Environ. Microbiol. 75: 1219-1219 [Full Text]