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AEM Accepts, published online ahead of print on 25 August 2006
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Appl. Environ. Microbiol. doi:10.1128/AEM.01374-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Simultaneous Biodetoxification of S, N and O Pollutants by Engineering a Carbazole-degrading Gene Cassette in a Recombinant Biocatalyst

Bo Yu, Cuiqing Ma, Wenjuan Zhou, Shanshan Zhu, Ying Wang, Jingyao Qu, Fuli Li, and Ping Xu*

State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People's Republic of China

* To whom correspondence should be addressed. Email: pingxu{at}sdu.edu.cn.


   Abstract

The gene cassette encoding enzymes responsible for degrading carbazole to anthranilic acid was introduced into a dibenzothiophene-degrader. The resultant strain Rhodococcus erythropolis XPDN could simultaneously transform the model pollutants of dibenzothiophene, carbazole and dibenzofuran to nontoxic metabolites and may have an application potential to bioremediation.




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