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AEM Accepts, published online ahead of print on 21 December 2007
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Appl. Environ. Microbiol. doi:10.1128/AEM.01958-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Adherence of Helicobacter pylori to abiotic surfaces is influenced by serum

John C Williams, Karla A McInnis, and Traci L Testerman*

LSU Health Sciences Center- Shreveport, Department of Microbiology and Immunology, 1501 Kings Hwy, Shreveport, LA 71130-3932

* To whom correspondence should be addressed. Email: tteste{at}lsuhsc.edu.


   Abstract

H. pylori cultured in chemically-defined medium without serum readily adhere to a variety of abiotic surfaces. Growth produces microcolonies that spread to cover the entire surface along with a planktonic subpopulation. Serum inhibits adherence. Initial attachment is protein-mediated, but other molecules are responsible for more permanent attachment.







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