AEM
Home Help [Feedback] [For Subscribers] [Archive] [Search] --
AEM Accepts, published online ahead of print on 8 February 2008
This Article
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
AEM.01998-07v1
74/7/2248    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Favilla, M.
Right arrow Articles by Altomare, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Favilla, M.
Right arrow Articles by Altomare, C.
Agricola
Right arrow Articles by Favilla, M.
Right arrow Articles by Altomare, C.

 Previous Article  |  Next Article 

Appl. Environ. Microbiol. doi:10.1128/AEM.01998-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Inhibition of species of the Aspergillus section Nigri and ochratoxin A production in grapes by fusapyrone

Mara Favilla, Michelangelo Pascale, Alessandra Ricelli, Antonio Evidente, Carmine Amalfitano, and Claudio Altomare*

Institute of Sciences of Food Production, CNR, 70125 Bari, Italy, and Dipartimento di Scienze del Suolo, della Pianta e dell'Ambiente, Università di Napoli Federico II, 80055 Portici, Italy

* To whom correspondence should be addressed. Email: claudio.altomare{at}ispa.cnr.it.


  Abstract

Fusapyrone (FP), an antifungal natural compound, was tested against the three main ochtatoxigenic species of the Aspergillus section Nigri. The minimal inhibition concentrations (MIC) at 24 h were 6.0, 11.6, and 9.9 µg/ml for A. carbonarius, A. tubingensis, and A. niger, respectively. Strong inhibition of growth and morphological changes were still observed at half MIC after 7 days. The application of a 100 µg/ml FP solution in a laboratory assay on artificially inoculated grapes resulted in a significant reduction of A. carbonarius CFU counts, up to 6 orders of magnitude. Dramatic reductions of the OTA content were obtained with application of either 100 or 50 µg/ml of FP (average amount of OTA, n=3 : 0.6 and 5.1 ng/g of grape, respectively), compared to positive control (112.5 ng/g).






Home Help [Feedback] [For Subscribers] [Archive] [Search] --
J. Bacteriol. Microbiol. Mol. Biol. Rev. Eukaryot. Cell All ASM Journals

Copyright © 2008 by the American Society for Microbiology. All rights reserved.