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Appl. Environ. Microbiol. doi:10.1128/AEM.02148-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Use of Murine Norovirus as a surrogate of human norovirus to evaluate resistance to disinfectants

Laboratoire de Virologie. Centre National de Référence des Virus Entériques. Centre Hospitalier Universitaire de Dijon. 7 boulevard Jeanne d'Arc. 21079 Dijon CEDEX. France

^* To whom correspondence should be addressed. Email: gael.belliot{at}u-bourgogne.fr.

	Abstract

The murine norovirus (MNV) was used as a surrogate to study human norovirus resistance to disinfectants used in hospitals. The MNV was sensitive to alcohol, alcohol hand rubs, bleach and povidone iodine-based disinfectant. Real-time RT-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.