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AEM Accepts, published online ahead of print on 29 February 2008
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Appl. Environ. Microbiol. doi:10.1128/AEM.02477-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Tracing Norovirus Outbreak Strains in Mussels collected near Sewage Effluents

Nancy P Nenonen*, Charles Hannoun, Peter Horal, Bodil Hernroth, and Tomas Bergström

The Department of Infectious Diseases/ClinicalVirology, University of Gothenburg, Guldhedsgatan 10b, 413 46 Gothenburg, Sweden; The Royal Swedish Academy of Sciences, Sven Loven Centre for Marine Sciences, Kristineberg 566, SE-450 34 Fiskebäckskil, Sweden

* To whom correspondence should be addressed. Email: nancy.nenonen{at}microbio.gu.se.


  Abstract

Noroviruses from mussels collected near sewage-effluents were compared with local patient outbreak strains. Sequence-analyses of RNA polymerase-capsid-polyA-3' (3.1kilobase) confirmed 99.9% similarity between genotype I.1 strains from mussels, and patient strains from recreational-bathing outbreaks; indicating the potential usefulness of sentinel norovirus mussel studies in tracing human norovirus contamination of coastal waters.




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