Cover photograph: Entangled cells of the Lyme disease spirochete Borrelia burgdorferi producing a green fluorescent protein as well as a fluorescently labeled lipoprotein (magenta). Localization of the lipoprotein at the middle and poles of the cells was discovered because of the development of molecular reagents. (See related article at e01824–18.) (Copyright © 2018 Takacs et al. CC-BY 4.0.)