TABLE 3.

MIC of purine analogs on M. acetivorans C2A and hpt1::mini-mar

Purine analogMIC (μg/ml)a
C2Ahpt1::mini-MAR
2-MP1.3110
8ADP1.74>74.5
6-Mercaptopurine5.67NTb
2,6-Diaminopurine24.6NT
6-Methylaminopurine107NT
2-Aminopurine>462NT
2-Mercaptopurine>462NT
2-Amino-6-methylmercaptopurine>462NT
  • a ca. 107 cells of the indicated strain were inoculated into HS-MA medium containing serial dilutions of a purine analog. Cultures were incubated at 37°C, and growth was scored after 14 days.

  • b NT, not tested.