TABLE 1.

Transcript levels of young (10 generations) and old (45 generations) aerobic, maltose-limited chemostat cultures of S. cerevisiae CEN.PK113-7D

EnzymeLocusTranscript levelaFold change (old vs young culture)P valueb
Systematic nameStandard nameYoung cultureOld culture
Maltose permeaseYGR289CMAL1120,015 ± 2,12724,930 ± 2481.20.19
YBR298CMAL3112,721 ± 81315,587 ± 1,0561.40.04
YDL247W258 ± 152430 ± 4551.70.69
YJR160C229 ± 85363 ± 1871.60.49
Total33,223 ± 228441,310 ± 1,1911.20.04
MaltaseYBR299WMAL3217,626 ± 31020,011 ± 4041.10.03
YJL221CFSP23,018 ± 5458,232 ± 2,2082.70.17
YGR287C1,698 ± 3845,059 ± 8633.00.08
YJL216C813 ± 2071,084 ± 371.30.31
Total23,155 ± 76434,386 ± 2,4051.50.00
Maltose activatorYGR288WMAL13282 ± 2337 ± 761.20.49
MAL23AcA
YBR297WMAL33865 ± 287834 ± 38−1.00.90
YPR196W2,863 ± 1063,670 ± 3781.30.18
YFL052WAA
Total3,728 ± 3064,504 ± 3801.20.15
  • a Average transcript levels and their mean deviations were calculated from two independent chemostat cultures.

  • b Determined by Student's t test (a P value of ≤0.05 is considered significant).

  • c A, transcript defined as absent by the algorithm implemented in version 4.01 of the Affymetrix Microarray Suite software.