TABLE 2.

L. reuteri 100-23 genes mutated in this study with examples of matches in database, similarity, and predicted function

Gene (bp)Similar protein(s)aOrganism% Identity/no. of amino acidsaFunction
msrB (429)Peptide methionine sulfoxide reductaseSeveral organisms71/140 (L. johnsonii)Reduction of oxidized methionine residues in proteins
xylA (1,350)Xylose isomeraseSeveral organisms81/447 (Lactobacillus brevis)Xylose utilization
met (1,137)Hypothetical proteinSeveral organisms48/368 (L. johnsonii)Unknown; low similarity (<25%) to methionine synthase II (cobalamin independent) of several organisms
lsp (5,905)LJ0621 L. johnsonii 83/1,073Unknown
COG2931 L. gasseri 25/1,687Unknown
Rlp L. fermentum 25/811Unknown
R28 Streptococcus pyogenes 25/550Adhesion to epithelial cells
Esp Enterococcus faecalis 24/611Biofilm formation
Bap S. aureus 20/1,611Biofilm formation
  • a BlastX results.