TABLE 1.

Significant GO terms and TIGR biological role categories from the EASE analysis

ExptSystemGene categoryEASE score
Iron reduction
    Up-regulatedTIGR roleCellular processes; detoxification1.27E−03
GO biological processMetal ion transport2.99E−03
GO biological processTransport3.76E−03
TIGR roleTransport and binding proteins; cations and iron-carrying compounds2.01E−03
    Down-regulatedGO molecular functionHeat shock protein activity1.43E−04
GO biological processProtein folding1.82E−04
TIGR roleProtein fate; protein folding and stabilization3.49E−04
Nitrogen fixation
    Up-regulatedTIGR roleCentral intermediary metabolism; nitrogen fixation1.06E−11
GO biological processNitrogen fixation1.15E−11
GO biological processNitrogen metabolism5.25E−10
TIGR roleTransport and binding proteins; anions1.07E−06
GO molecular functionOxidoreductase activity, acting on reduced ferredoxin as donor, dinitrogen as acceptor3.69E−05
GO biological processMolybdate ion transport3.69E−05
GO molecular functionNitrogenase activity3.69E−05
GO molecular functionOxidoreductase activity, acting on iron-sulfur proteins as donors5.98E−05
    Down-regulatedGO biological processOxidative phosphorylation, NADH to ubiquinone2.04E−06
GO molecular functionOxidoreductase activity, acting on NADH or NADPH6.11E−06
GO molecular functionOxidoreductase activity1.00E−05
GO molecular functionNADH dehydrogenase (ubiquinone) activity1.42E−05
GO molecular functionSodium ion transporter activity1.42E−05
GO molecular functionOxidoreductase activity, acting on NADH or NADPH, quinone, or similar compound as acceptor1.42E−05
GO molecular functionCarrier activity2.00E−05
TIGR roleEnergy metabolism; electron transport2.71E−05
GO molecular functionHeat shock protein activity4.12E−05
GO molecular functionHydrogen ion transporter activity9.62E−05