TABLE 2.

Inhibition of E. coli K-12 ATCC 25404 [R1drd19, pCM18] biofilms by the addition of ursolic acid in flow chambers

Time after inoculation (h)ConditionsMean ± SDa
Biomass (μm3/μm2)Substratum coverage (%)Mean thickness (μm)Roughness coefficient
22No ursolic acid38 ± 1240 ± 1053 ± 200.5 ± 0.2
10 μg of ursolic acid/ml3 ± 6 (1/10)2 ± 2 (1/20)4 ± 9 (1/14)1.8 ± 0.5 (3.6)
65No ursolic acid14 ± 610 ± 1022 ± 71.1 ± 0.3
10 μg of ursolic acid/ml3.2 ± 2 (1/4)4 ± 2 (1/2.5)7 ± 4 (1/3.2)1.5 ± 0.2 (1.3)
  • a The (10 μg of ursolic acid)/(no ursolic acid) ratios are given in parentheses.