TABLE 4.

JCVI role categories with over- or underrepresentation for σB-dependent genes

JCVI role categoryaNo. of annotated genesNo. of σB-dependent genesbFisher's exact test P valuecOdds ratiod
Cellular processes165350.04631.5
Energy metabolism380103<0.00012.3
DNA metabolism10280.02630.5
Regulatory functions226240.03610.6
Unknown function10990.03120.5
  • a JCVI L. monocytogenes EGD-e role categories.

  • b Number of σB-dependent genes in all lineage representatives for each role category.

  • c Fisher's exact test was used to identify significant associations between σB-dependent genes and the total number of genes in a role category; two-sided P values of <0.05 were considered significant.

  • d Odds ratios were calculated to characterize significant associations between σB-dependent genes and role category.