TABLE 1.

Annotation of the genes of the cyr cluster from Oscillatoria PCC 6506

GeneSize (aa)bBLAST similarity matchaGenBank accession no.Identity (%)
cyrD1,873Polyketide synthase (CyrD) (Cylindrospermopsis raciborskii AWT205)ABX60152.183
cyrC1,672Polyketide synthase (CyrC) (Cylindrospermopsis raciborskii AWT205)ABX60163.186
orf1152RimK domain protein ATP-grasp (Herpetosiphon aurantiacus ATCC 23779)ABX07651.141
cyrH473Aminohydrolase (CyrH) (Cylindrospermopsis raciborskii AWT205)ABX60158.191
trp1404Transposase, IS605 OrfB family (Cyanothece sp. strain PCC 7822)EDX96268.153
cyrK479Multidrug exporter MatE (CyrK) (Cylindrospermopsis raciborskii AWT205)ABX60156.190
cyrA398Amidinotransferase (CyrA) (Cylindrospermopsis raciborskii AWT205)ABX60160.186
cyrB2,957Mixed NRPSc/polyketide synthase (CyrB) (Cylindrospermopsis raciborskii AWT205)ABX60161.179
trp2299Transposase, IS605 family (Synechococcus sp. strain PCC 7335)EDX82555.156
cyrE1,893Polyketide synthase (CyrE) (Cylindrospermopsis raciborskii AWT205)ABX60162.184
cyrJ261Putative sulfotransferase (CyrJ) (Cylindrospermopsis raciborskii AWT205)ABX60159.185
cyrF1,368Polyketide synthase (CyrF) (Cylindrospermopsis raciborskii AWT205)ABX60153.184
cyrG478Putative uracil ring formation (CyrG) (Cylindrospermopsis raciborskii AWT205)ABX60154.188
cyrI277Proline dioxygenase-like protein (CyrI) (Cylindrospermopsis raciborskii AWT205)ABX60155.184
cyrN175Adenylylsulfate kinase (Trichodesmium erythraeum IMS101)ABG51178.174
  • a The BLAST searches were performed by using the online tools available at the National Center for Biotechnology Information website and using the GenBank database (January 2010).

  • b aa, amino acids.

  • c NRPS, nonribosomal peptide synthase.