TABLE 3.

Prevalence of bacterial isolates carrying tet genes in bacterial populations in wastewater and river water downstream

Mechanism of drug resistancebResistance genePrevalence of isolates (%) ina:
WWRWD
Effluxtet(A)69.362.1
tet(B)6.36.9
tet(C)42.921.8
tet(D)26.533.3
tet(E)2.10
tet(G)00
tet(H)0.51.1
tet(J)32.344.8
tet(Z)23.39.2
tet(30)2.69.2
tet(K)23.316.1
tet(L)37.631.0
tet(AP)11.612.6
tet(Y)22.227.6
Ribosomal protectiontet(M)12.218.4
tet(O)9.016.1
tet(S)6.333.3
tet(W)28.067.8
tet(Q)00
tet(T)4.25.7
otr(A)16.98.0
tet(BP)0.50
Enzymatic modificationtet(X)00
  • a WW, wastewater effluent; RWD, downstream river water.

  • b Efflux is the mechanism of utilizing energy-dependent membrane-associated efflux proteins which export tetracycline out of the cell; ribosomal protection is the mechanism of utilizing ribosomal protection proteins which interact with the ribosome and disrupt the tetracycline binding site; and enzymatic modification is the mechanism of utilizing tetracycline inactivation enzymes.