TABLE 1

Growth rates and generation times of the parent strain (ΔMAI), Δupp mutant, and upp complementation in trans with and without treatment with 5-FU

StrainGrowth rate (h−1)Generation time (h)
Without 5-FUWith 5-FUWithout 5-FUWith 5-FU
ΔMAI0.077 ± 0.0017NAa9.1 ± 0.2NA
ΔMAI Δupp0.079 ± 0.00170.070 ± 0.00408.8 ± 0.210.0 ± 0.6
ΔMAI Δupp/upp+0.076 ± 0.0041NA9.1 ± 0.5NA
  • a NA, not applicable.