TABLE 4

Differentially abundant proteins identified through comparison of D. simulans ovarian proteomesa

Functional classificationProteinRelative abundance
wRi/CuredwMel/CuredwMel/wRi
Carbohydrate transport and metabolismGlycogen phosphorylase1.0971.8841.717
Chromatin structure and dynamicsHistone H40.9130.6450.706
Cytoskeleton and cell motilityTropomyosin 21.0811.7011.573
Energy production and conversionATP synthase, δ subunit1.6871.1200.664
Function unknownFemale-specific independent of transformer0.7853.3594.277
Lipid transport and metabolismCG3902 (acyl-CoA dehydrogenase activity)1.6511.6640.974
Retinoid- and fatty acid-binding glycoprotein2.1752.3851.008
Yolk protein 11.4071.9901.414
Yolk protein 21.4001.6931.209
Protein modification, folding, and turnoverHeat shock protein 261.1931.7531.469
Heat shock protein 270.6311.2992.058
Tripeptidyl-peptidase II0.7011.2301.755
RNA binding, processing, and modificationFibrillarin1.0890.4880.448
Squid0.5690.6771.191
Translation, ribosomal structure, and biogenesisRibosomal protein L320.9570.6510.654
Ribosomal protein L34b0.6540.5930.906
Ribosomal protein S250.9620.6290.680
  • a Relative abundance represents a ratio of average LFQ scores for each sample type: Dsim wRi/Dsim Cured, Dsim wMel/Dsim Cured, and Dsim wMel/Dsim wRi. Ratios that indicate up- or downregulation are indicated in boldface type. CoA, coenzyme A.