Table 2.

Bioactivity evaluation of the compound 4-TMP-DMEP

CompoundEC50 (μM)aLog P
HL-60K-562HepG2KBBGC-823HK-2
4-TMP-DMEP0.240.200.130.120.110.400.66
DMEP0.310.320.370.43398.0538.730.57
PTOX<0.01<0.01<0.01<0.10529.66<0.010.34
  • a The values are averages of data in triplicate. For MTT methods, the drug exposure period was 48 h.