Table 3

Phage growth parameters with or without antibiotic pretreatment of S. aureus ATCC 43300

Antibiotic (μg/ml)Growth curve parameter (mean ± SD)
Time (min) for:Burst size (no. of phage/cell)
AdsorptionLatent periodPlaque enlargement period
Control21.3 ± 1.1533.3 ± 2.821.7 ± 2.8051.7 ± 1.23
Linezolid (1)14.6 ± 1.12b16.6 ± 2.6b26.6 ± 2.5b58.6 ± 1.10b
Tetracycline (0.25)15.3 ± 1.15b18.3 ± 2.90b26.6 ± 2.60b57.4 ± 1.05b
Clarithromycin (4)17.4 ± 1.11b23.4 ± 2.89b28.3 ± 2.2b54.7 ± 0.45b
Telithromycin (4)18.6 ± 1.12b23.4 ± 2.82b28.3 ± 2.30b54.1 ± 0.8b
  • a Values are means ± standard deviations of three values.

  • b Data have P values of <0.05, which is considered statistically significant.