Table 2

Cyto- and phototoxic effects of IA derivatives on C. albicans planktonic cultures

IA derivativeLight dose (J/cm2)Log10 reduction in survival at IA concn (μM) ofa:
01050100
C131100.00.00.10.0
1000.20.20.20.2
2000.10.30.30.3
C133000.00.10.10.3
1000.3 1.6 2.9 6.1
2000.3 2.2 3.1 6.1
C137500.00.10.10.3
1000.30.30.30.3
2000.10.20.30.2
C141500.00.00.00.0
1000.20.7 1.6 1.7
2000.0 1.0 1.9 3.6
C155800.00.20.30.3
1000.20.6 1.1 2.1
2000.20.40.3 2.9
  • a The values were calculated by subtracting log10 CFU/ml of tested samples from those of untreated controls (0 J/cm2; 0 μM IA). Shading indicates dark toxicity (samples treated with PS in the dark). Underlined values indicate noticeable phototoxicity.