Table 3

Substrate-specific biomass yield (YX/S), final titer, substrate-specific l-lysine yield (YP/S), and biomass-specific production rate (qP) of C. glutamicum l-lysine producers cultivated in CGXII medium with 4% (wt/vol) glucose and 0.5% (wt/vol) BHI in shake flasks (DM1800) or in bioreactors (DM1933)a

StrainYX/S (g CDW/mmol glucose)Titer (mM l-lysine)YP/S (mol l-lysine/mol glucose)qP [g l-lysine/(g CDW × h)]
C. glutamicum DM18000.072 ± 0.00122 ± 20.10 ± 0.010.068 ± 0.007
C. glutamicum DM1800 aceE A160.048 ± 0.00145 ± 20.20 ± 0.020.091 ± 0.009
C. glutamicum DM19330.069 ± 0.00435 ± 30.16 ± 0.030.078 ± 0.016
C. glutamicum DM1933 aceE A160.043 ± 0.00652 ± 60.23 ± 0.040.138 ± 0.028
  • a Values represent the arithmetic mean ± standard deviation from three independent experiments.